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Smoking he said was the most important public health issue of our time. He made it a truly national issue, used his bully pulpit to get on radio and TV and emphasize the dangers of secondhand smoke

Indeed, with profits rivaling those of narcotics, and relatively light penalties, the business is fast reinventing itself

103,104 Considerable evidence exist that aromatic amines such as 4-aminobiphenyl and 2-naphthylamine are potent bladder carcinogens, and smokers are known to be at an elevated risk of bladder cancer, so these are presumed to be the primary causative agents

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